![]() ![]() The results of PFT and further clinical tests were taken from the patient’s records. Differences in these parameters between inspiration and expiration were calculated (Vol. QCT parameters included lung volume, total emphysema score (TES, ie, the emphysema index) and the 15th percentile of lung attenuation (P15) for the whole lung and each lobe separately. In our retrospective study, results from three time points were compared: Before EBV implantation (BL), after EBV implantation (TP2), and after EBV explantation (TP3). A total of 10 of these 41 patients ventured a second attempt at EBV therapy and underwent complete reevaluation. In 41 of these 274 patients, EBV treatment was unsuccessful and the valves had to be removed for various reasons. Prior to intervention, a complete evaluation was performed that included quantitative computed tomography analysis (QCT) of scans acquired at full inspiration and full expiration, pulmonary function tests (PFT), and paraclinical findings (6-minute walking distance test (6MWDT) and quality of life questionnaires). Patients and Methods: Our hospital’s medical records listed 274 patients with high-grade COPD (GOLD stages 3 and 4) and pulmonary emphysema who were treated with EBV to reduce lung volume. Purpose: To investigate changes in quantitative CT analysis (QCT) and pulmonary function tests (PFT) in pulmonary emphysema patients who required premature removal of endobronchial valves (EBV). Jonas Alexander Leppig, 1 Lan Song, 2 Dorothea C Voigt, 1 Felix W Feldhaus, 1 Christoph Ruwwe-Gloesenkamp, 3 Jacopo Saccomanno, 3 Bianca C Lassen-Schmidt, 4 Konrad Neumann, 5 Katja Leitner, 6 Ralf H Hubner, 3 Felix Doellinger 1ġDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany 2Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China 3Department of Internal Medicine/Infectious Diseases and Respiratory Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany 4Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany 5Institute of Biometrics and Clinical Epidemiology, Charité Universitätsmedizin Berlin, Berlin, Germany 6Department of Internal Medicine, Kantonsspital Aarau AG, Aarau, SwitzerlandĬorrespondence: Jonas Alexander Leppig, Department of Radiology, Charité Universitätsmedizin Berlin, Charité Campus Virchow-Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany, Tel + 49 30 450 627 283, Fax + 49 30 450 527 911, Email ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |